Potential Inhibition by Phaleria macrocarpa Leaves Ethanol Extract on Ki-67 Expression in Distal Colon Mouse
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چکیده
منابع مشابه
Wound-healing potential of the fruit extract of Phaleria macrocarpa.
The wound-healing potential of Phaleria macrocarpa was evaluated by monitoring the levels of inflammatory mediators, collagen, and antioxidant enzymes. Experimentally, two-centimeter-wide full-thickness-deep skin excision wounds were created on the posterior neck area of the rats. The wounds were topically treated with gum acacia as a vehicle in the control group, intrasite gel in the reference...
متن کاملBioassay-guided antidiabetic study of Phaleria macrocarpa fruit extract.
An earlier anti-hyperglycemic study with serial crude extracts of Phaleria macrocarpa (PM) fruit indicated methanol extract (ME) as the most effective. In the present investigation, the methanol extract was further fractionated to obtain chloroform (CF), ethyl acetate (EAF), n-butanol (NBF) and aqueous (AF) fractions, which were tested for antidiabetic activity. The NBF reduced blood glucose (p...
متن کاملAntioxidant activities and tyrosinase inhibition effects of Phaleria macrocarpa extracts.
BACKGROUND The ethyl acetate and chloroform extracts of stems, leaves and fruits of Phaleria macrocarpa were screened for their antioxidant capacity and tyrosinase inhibition properties. MATERIAL AND METHOD The total phenolic content (TPC), 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging and ferric-ion reducing power (FRAP) were used to evaluate their antioxidant capacity. Tyrosi...
متن کاملEffect of Phaleria macrocarpa on Sperm Characteristics in Adult Rats.
PURPOSE The purpose of this study was to determine the effects of Phaleria macrocarpa (PM) on male fertility by assessing its effect on the sperm characteristics which included the sperm count, motility, viability and morphology. METHODS Eighteen male rats were equally divided into three groups. Each group of rats was orally supplemented for 7 weeks either with PM aqueous extract (240 mg/kg),...
متن کاملInvolvement of Inflammatory Mediators in the Gastroprotective Action of Phaleria macrocarpa against Ethanol-Induced Gastric Ulcer
This research aimed to determine the potential protective effects ofPhaleria macrocarpafruit extracton rat gastric mucosal injury induced by ethanol andto clarify the roles of prostaglandinE2 (PGE2), transforming growth factor1 (TGF) and tumor necrosis factorTNF). Main methods: Seven groups of rats were orally pretreated with Tween20 as vehicle control group; Tween20 as ulcer group; 20 mg/kg of...
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ژورنال
عنوان ژورنال: Pharmacognosy Journal
سال: 2020
ISSN: 0975-3575
DOI: 10.5530/pj.2021.13.56